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Tracking the Bioreduction of Disulfide‐Containing Cationic Dendrimers

Identifieur interne : 001327 ( Main/Exploration ); précédent : 001326; suivant : 001328

Tracking the Bioreduction of Disulfide‐Containing Cationic Dendrimers

Auteurs : Lorine Brülisauer [Suisse] ; Nadia Kathriner [Suisse] ; Mark Prenrecaj [Suisse] ; Marc A. Gauthier [Suisse] ; Jean-Christophe Leroux [Suisse]

Source :

RBID : ISTEX:27E6C713D288C248E6D81ADA81CE5CF463BBA720

English descriptors

Abstract

Disulfide erhöhen die Transfektionseffizienz und vermindern die Toxizität kationischer Polymere für den Gentransport. Eine quantitative Analyse der biologischen Reduktion eines dendritischen Polykations in vier Zelllinien liefert wichtige Informationen für das Verständnis und die Optimierung biologisch reduzierbarer Wirkstoff‐ und Gentransportsysteme.

Url:
DOI: 10.1002/ange.201207070


Affiliations:


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Le document en format XML

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